Medicines

Lactobacillus preparations for intestinal preparations

What is the significance of lactobacilli and bifidobacteria for the intestines? A healthy climate in the intestines affects the state of the whole human body. Lacto-and bifidobacteria strengthen and restore the intestinal microflora. Today the release of such funds is diverse. For effective treatment and prevention it is important to choose the right means.

What do intestines need live bacteria for?

Live bacteria for the intestines are very important and necessary components both for it and for all internal systems of the body. First of all, they perform supporting functions and are intended for normal functioning of the digestive tract. In the intestines live different bacterial organisms: from beneficial to harmful. Lactic acid bacteria and bifidobacteria are among the most numerous members of the beneficial intestinal compound. Ratios with harmful bacteria should be 1: 100. When imbalance appears unpleasant symptoms in the form of: violation of the chair, flatulence, pain, fatigue and reduced immunity.

Healthy microflora (beneficial bacteria) is involved in such processes of the gastrointestinal system:

digests food with enzymes (neutralization of fatty acids, carbohydrate fermentation, protein hydrolysis, fiber dissolution), formation of an acidic environment in the intestine (preventing the multiplication of pathogenic microbes), absorbs vitamins and synthesizes them, prevents toxic substances from the body, strengthens the immune system, increases peristalsis in the intestines, participates in the metabolism of cholesterol and bile acid (the presence of bile acid slows down the processes of absorption of fluid in the intestine, as a result, the norm izuetsya chair).

Difference of bifidobacteria and lactobacilli

Lactobacilli is a type of bacteria that lives throughout the human digestive tract.

Lactobacilli - gram-positive optional anaerobic (microaerophilic) bacteria. Their habitat is the digestive system and the vagina. Lactobacilli are able to produce a large number of elements, and they, in turn, are involved in the work of metabolic processes of the body. Also, these bacteria are involved in the breakdown of plant foods, turning it into lactose (lactic acid) and carbohydrates. With the help of the resulting acidic environment, the growth and development of fungi and pathogenic bacteria is blocked.

Bifidobacteria are Gram-positive anaerobic bacteria, in the form of curved rods. There are 80-90% of the intestinal microflora of children who are breastfed. After the end of breast feeding, the intestinal microflora of children changes and becomes similar to an adult. The habitat of bifidobacteria is the colon, they help break down carbohydrates, stop the development of pathogenic and putrefactive microbes, create obstacles for toxic and other harmful substances to enter the human body, are a preventive measure of allergic reactions, are also an overwhelming factor in the formation of carcinogenic substances.

Preparations for the intestine with lactobacilli

To date, a large number of various tools that contain lactic acid bacteria. These tools help to restore the natural environment in the intestines. It happens as a drug, and in the form of a dietary supplement. All of them normalize the natural microflora of the gastrointestinal system, treat diseases caused by a lack of lactobacilli in the intestine.

Probiotic "Atsipol"

The composition of this drug consists of kefir fungi and lactobacilli.The form of release in the form of capsules, which is preferable due to the protection of microorganisms shell from the effects of gastric juices, as a result, their dissolution occurs in the intestine. From this it follows that all lactobacilli get to the designated place (intestine), providing a speedy recovery and balancing condition.

Probiotic "Atzilak"

The composition of the drug contains acidophilic lactic acid bacteria, is a universal tool for restoring the normal microflora of the internal systems of a person, has a pronounced antimicrobial effect, allowing the simultaneous elimination of pathogens of various infectious diseases.

Drug "Lactobacterin"

Lactobacterin is a probiotic that improves digestion and normalizes the body's defenses.

The composition includes live acidophilic bacteria and contributes to the increase of acidity in the internal environment. With the help of this destroyed harmful microorganisms, trapped in the human body. A positive effect was noted in metabolic processes, improvement of digestion, and normalization of the body's defenses.

Drugs, including Bifidobacterium

Great variety of tools with bifidobacteria. The focus of all probiotics with the content of bifidobacteria is the same, distinctive features are present in the name, manufacturer and in the form of release. They come in the form of: capsules, suppositories, powders, and in liquid form. Let us consider in more detail the advantages of these forms.

Capsules and Candles

Capsules are the best and because of this expensive forms of release. This is due to these advantages: they can be stored at room temperature, the capsular membrane protects bacteria from destruction in the juices of the stomach (facilitates the accelerated restoration of microflora), contains several types of bacteria in their composition, is effective when combined with antibacterial drugs, can be consumed regardless of the meal . These include such drugs: Linex, Bifikol, Bifidumbakterin and others. The use of candles, in most cases, is used for gynecological reasons. Among the candles with bifidobacteria can be distinguished: "Bifonorm", "Bifidumbakterin."

Probiotics in powder form

Powder products (dry) attract with their low price. However, there are a number of drawbacks: the composition is limited to one type of bacterium, the joint intake with antibiotics reduces the effectiveness of the powder preparation, some components of the preparation are destroyed by the action of the juices of the stomach. By dry means include: "Bifidumbakterin", "Kolibakterin."

Liquid Probiotic Forms

Liquid forms of probiotics do not need to be diluted and should be taken half an hour before eating.

Probiotic in liquid form is in the middle price range. They include, in addition to bifidobacteria, trace elements that are able to attach beneficial bacteria to the intestinal walls. This form does not need to be diluted, the effectiveness is noted during simultaneous administration with antibacterial drugs. The disadvantages of the liquid form include: strict storage in the refrigerator, some destruction of microelements in the juices of the stomach and the taking of funds should be carried out only half an hour before eating. In liquid form produced: "Biovestin", "Florist".

What are symbiotics?

What probiotics to choose? You can follow the recommendations: if the violation of the functioning of the intestine manifests itself in constipation, you should take money with lactic acid bacteria in the composition. For diarrhea use better varieties of agents with bifidobacteria. This recommendation is not universal. In order not to make a mistake, you can stop the choice on the combined preparation. The name "symbiotics" comes from the word symbiosis. It follows from this that symbiotics are drugs in which lacto-and bifidobacteria coexist at the same time.The most famous are: Linex, Symbiolact Compositum, Florin Forte, RioFlora Immuno Neo. All drugs have similar effects of correction and indications.

Preparations for children

Probiotics with bifidobacteria or lactobacilli are recommended to be given to children for prevention. However, for any signs of disorder in the child’s gastrointestinal tract (diarrhea, constipation, flatulence, obvious rumbling in the abdomen, pain), the use of drugs of this type is prescribed for regular use. It is recommended to take 30 minutes before eating and to strictly follow the dosage prescribed by the doctor. Probiotics prescribed for children: “Lactobacterin”, “Linex”, “Bifilact”, “Bifilin”, “Bifidumbacterin”.

Waiting from reception

The use of funds with bifidobacteria and lactobacilli effectively solve a lot of problem states of the body. When receiving these funds, the normal functioning of the gastrointestinal system is resumed, inflammatory processes in other internal organs of the human body are mitigated, a marked increase in immunity and a positive effect on the course of allergic reactions. When making a choice of probiotics, you should familiarize yourself with the instructions in detail and pay special attention to contraindications to their use. It should be remembered that any medicine must be prescribed by a specialist and taken under its control.

General characteristics of eubioticsPreparations with lactobacilliDrugs of the family of bifidobacteriaSimbiotics with lactobacteria and bifidobacteria

Healthy intestinal microflora is a guarantee of health and beauty. To restore the balance of microflora help bifidobacteria and lactobacilli, drugs, which flooded the market in recent decades. In order to achieve a stable therapeutic effect, one should competently choose a drug with live microorganisms, based on its composition and range of problems to be solved.

General characteristics of eubiotics

Bifidobacteria and lactobacilli are representatives of the intestinal microflora of healthy people and belong to the eubiotics, which belong to the group of probiotics. Probiotics include, along with representatives of healthy microflora, any microorganisms that have a beneficial effect on the intestines and the organism as a whole. Getting into the intestine, eubiotics by active reproduction and the creation of an acidic environment around themselves destroy pathogenic microorganisms.

Bifidobacteria processes the processing of B vitamins and the production of organic acids, without which the full absorption of useful substances is impossible. Preparations with bifidobacteria should not be used along with antibiotics, since the latter do not allow the reproduction of beneficial microorganisms. It is necessary to maintain an interval of 3-4 hours between taking medications.

Lactobacilli (lactobacilli) are responsible for the production of lactic acid and the maintenance of immunity. When taking antibiotics, it is necessary to use lactobacilli, since these drugs contribute to the normalization of microflora and do not have a mutually exclusive effect on antibiotics.

Eubiotics are used to treat and prevent dysbiosis, intestinal dysfunctions, intestinal infections, and diseases of the female genital tract. Some drugs are indicated for diseases of the urogenital system and ENT organs, with a weakened immunity. Exact indications for use depend on the composition of the drug and the form of release, in each case it is necessary to carefully study the instructions. It is also important to remember that many eubiotics have a limited shelf life in conditions of low temperature.

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Lactic acid bacteria preparations

Lactobacilli are present in all parts of the digestive and genital tracts. There are lactobacilli in the following drugs:

Atsilakt. Narine Acipol. Lactobacterin.

Acylact contains lactobacillus acidophilus species and is characterized by increased acid-forming ability. Available in the form of candles, lyophilisate for the preparation of suspensions, tablets. Atsilakt has a reduced lactose content, so it is successfully used to treat people with milk intolerance.

Narine contains acidophilic lactobacilli, is available in the form of capsules, tablets and powder. The drug is recommended as a biologically active food supplement for intestinal dysfunction, diseases of the upper respiratory tract and the genitourinary system. Narine in the form of capsules and tablets is taken orally before eating, the powder is used to make homemade yogurt.

Atsipol contains lactobacilli and kefir fungi, inactivated by heating. The drug has a convenient form of capsules, which are taken orally half an hour before meals. Children under 3 years old can take the drug just before a meal: you need to open the capsule, mix the contents with water or milk.

Lactobacterin contains planactum lactobacillus species that have an antagonistic effect on conditionally pathogenic and pathogenic microorganisms. For intestinal dysfunction, the drug is taken orally (tablets) before meals, for diseases of the female genitalia - intravaginally (candles).

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Drugs of the bifidobacterium family

Preparations containing bifidobacteria are used to normalize the intestinal microflora in children and adults. Different medicines from each other form of release and type of bifidobacteria in the composition. The following drugs are successfully used:

Bifilis Bifidumbacterin. Biovestin lacto.

Bifilis (Vigel) contains bifidobacteria of the species bifidum and lysozyme, which provides immunomodulatory, anti-inflammatory, bifidogenic and antimicrobial action. The drug is available in the form of bottles, the contents of which are filled with water, infused for several minutes, shaken and consumed inside 30 minutes before a meal.

Bifidumbacterin contains bifidobacteria of the species bifidum, which predominate in the intestines of newborns. Bifidumbacterin can be used for the correction of intestinal biocenosis in children and adults, as well as for prevention. Before use, the drug must be dissolved in a liquid: in water or dairy products. Bifidobacteria for newborns are dissolved in breast milk. Bifidumbacterin in candles is used to treat gynecological diseases (bacterial colpitis and vaginosis, a violation of the purity of the vagina) and intestinal dysfunction with lesions of the distal parts.

Biovestin-lacto is characterized by a high antagonistic ability with respect to pathogenic microorganisms due to the content of adolescentis in the composition of bifidobacteria. Biovestin-lacto is one of the few drugs with bifidobacteria that can be used simultaneously with antibiotics.

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Symbiotics with lactobacilli and bifidobacteria

Many drugs and dietary supplements to normalize healthy intestinal microflora are symbiotics and contain both bifidobacteria and lactobacilli. These drugs include:

Linex. Symbiolact compositum. Florin Forte RioFlora Immuno Neo.

Linex contains live acidophilic lactobacilli and bifidobacteria bifidum, enterococci. The drug is valid for use in infants, women during pregnancy and lactation. Linex is allowed to take in combination with chemotherapeutic drugs and antibiotics.

Symbiolact compositum contains a mixture of cultures of probiotic and lactic acid microorganisms: Lactobacillus caseus, acidophilic lactobacilli, bifidobacterium bifidum, bifidobacterium lactis, lactobacilli salivarius, lactococci lactis. Symbiolact compositum is produced in the form of a powder, taken orally with food.In the treatment of gynecological diseases in women, the drug is applied intravaginally by administering a tampon moistened with a solution of powder.

Florin Forte is used to normalize intestinal microflora, contains bifidobacterium bifidum and plantarum lactobacillus adsorbed on activated carbon. The drug in powder form should be taken orally with food. When treating with antibiotics, the interval between medications should be 3-4 hours.

RioFlora Immuno Neo contains a balanced combination of lactobacilli and bifidobacteria that strengthen the immune system, prevent the development of intestinal disorders.

The drug is recommended as a dietary supplement for people who do not have contraindications: age up to 3 years, individual intolerance to components, including lactose and soy.

Medicines, the content of lactobacilli and bifidobacteria, can effectively solve a whole range of problems associated with disorders in the gastrointestinal tract and inflammatory processes of other organs. When choosing a drug, you must carefully study the instructions, a list of indications and contraindications. It is especially necessary to be people with intolerance to milk, since eubiotics often contain lactose.

Probiotics (eubiotics) are living microorganisms that are the normal flora of the human intestinal tract. These are non-pathogenic, that is, beneficial bacteria, yeasts that have resistance to conditionally pathogenic or pathogenic microorganisms. They perform a lot of useful functions in the intestinal tract, produce biotin, folic acid, vitamin K, ensure the restoration of normal microflora in the mucous membranes of the human body and in the gastrointestinal tract, strengthen the immune system, protect from the effects of toxic substances.

Therefore, changes in the qualitative and quantitative composition of the microbiocenosis in the intestine, imbalance, dysbiosis, lead to various serious diseases in children and adults. With such clinical syndromes as antibiotic-associated diarrhea, as well as with SARS, influenza, the effect of the use of probiotics, analogs of Linex has been proven (instructions for use). However, according to the Gastroenterological Association of the USA, today there is not enough scientific research and data confirming which probiotic from the list of drugs in this group is most appropriate for the treatment of specific diseases or conditions of the body.

Today, probiotics for children are used mainly in the following conditions and diseases:

Diarrhea caused by taking antibiotics - in this case Enterol is considered one of the best probiotic preparations. Its members, Saccharomyces boulardii, stop antibiotic-associated diarrhea and prevent relapses. Diarrhea caused by infections, especially in children with rotavirus infection, in this case, the use of the lactobacilli Lactobacillus casei and Lactobacillus rhamnosus is most preferable. Irritable bowel syndrome - in this case, combined probiotics, as well as monocomponent lactobacteria and bifidobacteria, help to normalize bowel movements.

Classification of probiotics for children and adults

There are several generations of drugs that normalize the intestinal microflora:

1st generation is monocomponent drugs that contain only 1 bacterial strain - colibacterin, lactobacterin, bifidumbacterin 2 generation - self-eliminating antagonists - sporobacterin, biosporin, baktisubtil 3 generation - multicomponent preparations that include a combination of several strains of bacteria and additives - Linex, analogs Atsipol, Bifiliz, Atsilakt, Bifiform, etc.4th generation - sorbed bifidobacteria-containing probiotics, these are live bacteria of normal flora immobilized on a sorbent - Probifor, Bifidumbacterin Forte, Florin Forte.

Probiotics are also divided by the type of bacteria that make up them. Almost all probiotics are produced in Russia, with the exception of foreign analogues Linex, Enterol, Bifiform.

Unfortunately, almost 20% of the tested expensive dietary supplements do not contain the number of useful, living microorganisms stated on the label, some production strains are not capable of long-term colonization, since they are not adapted to the human body. A big disadvantage of imported probiotics is the presence of bacterial strains in them, which are not adapted for the population of people living in Russia and Ukraine.

Probiotics - 1st generation drug list

When dysbacteriosis 1 degree in a child, bifidumbacterin and lactobacterin can be used to correct microflora and prevent diseases. However, in acute intestinal infections, these probiotics should be combined with sorbents and other biologics. Such a drug as Colibacterin is usually used for torpid flow colitis, therefore it is practically not used for the treatment of children.

Dry drugs before use dissolve in boiled cool water 1 dose -1 tsp a spoonful of water, the prepared solution is taken immediately half an hour before meals 2-3 p / day.

Colibacterin dry

Release form: lyophilisate for solution preparation. Composition: live bacteria of E. coli strain M17 dried in a culture medium, with the addition of a gelatin-sucrose protective mixture

It is logical to add Biobacton and its analogues to this list of monodrugs, since it includes only an acidophilus bacillus active against opportunistic and pathogenic microorganisms. Although chronologically, Biobacton cannot belong to the 1st generation of probiotics - it is a more modern drug. It is recommended for the treatment of children from birth with viral-bacterial intestinal infections, intestinal dysbacteriosis, and antibiotics.

Probiotics 2 generations for children

The composition of probiotics 2 generations include yeast-like mushrooms and bacillus spores. Although spore bacilli and fungi are not part of the microflora, however, when ingested, they are able to perform the functions of beneficial bacteria - they suppress pathogenic microorganisms. Self-eliminating antagonists are recommended for children with acute non-infectious diarrhea, as well as with mild forms of intestinal infections and with subcompensated dysbacteriosis. The course of treatment should not be more than 5-7 days, in the future, probiotics from normal microflora should be connected to therapy.

Flivivin BS, Baktusubtil - they contain spores of bacillus B. cereus IP 5832, which are able to exhibit a broad spectrum of antibacterial properties, providing antidiarrheal and antimicrobial action. These spores are fairly resistant to the effects of gastric juice, and their transition to vegetative forms is produced in the intestine, restoring its microflora. Sporobacterin and bactisporin - contain Bacillus subtilis hay bacterium 3H, it is a live antagonist active strain, selected for the property of chromosomal resistance to the antibiotic rimfapicin. Enterol - contains yeast-like fungi saccharomycetes, it is indicated for the treatment of diarrhea while taking antibiotics, because its activity against clostridia has been proven vitamins and minerals.

Sporobacterin

Release form: suspension, lyophilisate Ingredients: live active strain Bacillus subtilis, resistant to antibiotic - rimphapicin Manufacturer - Russia

Price: 250-300 rubles.

Product form: tablets and lyophilisate Ingredients: aerobic saprophytes of the genus Bacillus (dried strains): B. Subtilis and B. Licheniformis. Manufacturer - Russia

Release form: capsules, suspension Composition: Boulardii lyophilized sugar cubicles, lactose monohydrate, gelatin, magnesium stearate, titanium dioxide Manufacturer - France

Price: 10 capsules 210 rubles. 30 pieces 420 rub., Suspension 230 rub.

Release form: powder Structure: it is dietary supplement, Saccharomyces cerevisiae - inactivated yeast culture, vitamins, dietary fiber, amino acids, microelements Manufacturer - Russia

Price: 60 pack. 300 rub.

Probiotics 3 generations - analogs of Linex

The list of probiotic 3 generations is a combination of drugs, that is, they can consist of several symbiotic strains of one type of bacteria - Acipol, Acilact, or different types - Linex, Bifiform. At the same time, there is an increase in the action of bacteria, moreover, other active substances are added to many combination drugs that can also enhance the effectiveness of the probiotic.

For example, a kefir fungus polysaccharide is added to Atsipol, lysozyme or lactose monosaccharide is added to the Bifiliz, and lactulose is added to the Bifiform. Such drugs are used to treat moderate severity of acute intestinal infections, in severe forms they are used as part of complex therapy.

Release form: capsules for children Linex Sachet (BAA), Linex Baby powder, Linex capsules Ingredients: bifidobacteria, enterococci, lactobacilli Manufacturer - Slovenia

Price: 16 capsules. 250 rubles, Baby powder 300 rubles, Linex for children Sasha 10 pcs. 370 rub. Linex immuno 30 caps. 500 rub.

Release form: Baby drops, Kids chewable tablets, Kompeks, Baby Ingredients: Baby - bifidobacteria, enterococci, Kids and Baby - additionally vitamin B1, B6, Complex - also inulin plant fiber Producer - Denmark

Price: Baby drops 400 rubles. Bifiform Kids, Kid 350 rub., Capsules Bifiform 30 pcs 300 rub.

Release form: rectal suppositories, lyophilisate for suspension preparation. Ingredients: Bifidobacterium bifidum, Lysozyme Manufacturer - Russia

Price 400-560 rubles.

Release form: capsules, tablets, lyophilisate Ingredients: kefiric fungi and lactobacillus acidophilus Producer - Russia

Price: 250-280 rubles.

Release form: tablets, lyophilisate for preparation of suspension, suppositories Ingredients: Lactobacillus acidophilic Producer - Russia

Price: 10 bottles of 5 doses of 330 rubles.

4th generation probiotics

Such drugs include - Probiform, Florin Forte and Bifidumbacterin Forte. Their difference is that these are sorbed probiotics, which include bifidobacteria immobilized on particles of activated ground coal, they have a stronger protective effect than conventional counterparts.

Bifidumbacterin forte is actively used in acute respiratory viral infections, having a detoxification effect, with various gastroenterological diseases, with dysbacteriosis of varying severity. However, it is contraindicated in children with lactase deficiency, and is also not used for gastroenteritis caused by rotavirus infection.

Probifor is considered a very effective antidiarrheal and detoxifying agent, the best probiotic. This is an enhanced form, since the number of bifidobacteria in it is significantly greater (10 times) than in Bifidumbacterin forte.

It is used even for severe forms of acute intestinal infection as the only drug for etiotropic therapy, as well as for dysbacteriosis, for diseases of the colon. Studies conducted to determine its effectiveness in shigellosis have shown that its effect is comparable to the effect of the use of fluoroquinolones (antibiotics), but without side effects. Probifor stops diarrhea in patients in intensive care units as effectively as the joint intake of Enterol and Bifiliz in 2-3 days.

Release form: powder, capsules Ingredients: Bifidobacterium bifidum, adsorbed on activated carbon Manufacturer - Russia

Price: powder 6 pcs 350 rub. 10 pieces 500 rub, 30 pieces 1400 rub. capsules 10 pcs 530 rubles.

Synbiotics - combination drugs

Synbiotics are combined dietary supplements that contain both probiotics and prebiotics. One of such means is - BAA Maksilak. It contains a prebiotic component - oligofructose and 9 cultures of beneficial bacteria. Among the beneficial bacteria are:

1 steptokokk, 1 lactococcus 3 cultures of bifidobacteria 4 cultures of lactobacilli

Of the 9 beneficial bacteria, 7 cultures make up the “normal” microflora of the gastrointestinal tract, performing all the functions of the intestinal microflora of its own intestinal microflora. Other cultures that are part of Maksilak are not natural inhabitants of the microflora of the human large intestine and small intestine, but they effectively affect many diseases of the gastrointestinal tract, as well as the respiratory and immune systems.

Manufacturer: Poland Price 10 caps. 300-360 rub.

Treatment of children with probiotics - which drug to choose?

Which probiotic is better for a child? Choosing the best probiotics for treating children in each specific clinical case for various nosological diseases is not an easy task for the doctor. In childhood, it is very important to apply probiotics rationally and the choice from the list of drugs depends on the type of lesion, the severity of the disease and the degree of intestinal microflora violation.

Probiotics for newborns. For newborns, premature infants up to a year for the treatment of intestinal dysbiosis (restoration of intestinal microflora after treatment of Staphylococcus aureus or Klebsiella), the cessation of diarrhea, the general improvement of physical condition and development, the following drugs are recommended:

Linex, Acipol, Lactobacterin, Bifidumbacterin forte - 14-28 days Probifor - with a course of therapy 7-10 days Bifiliz - 7-14 days

Respiratory diseases - SARS, infectious mononucleosis in children, pneumonia, bronchitis, false croup (barking cough in a child) - the same drugs in short courses, no more than 5 days.

Viral hepatitis - increased doses of 5-10 powders Bifidumbacterin forte 3-6 p / day or 1 powder of Probifor 2-3 p / day in a course of 5-7 days.

Allergic reactions, dermatosis in children - Azilakt, Lactobacterin, Bifidumbacterin forte 2-3 weeks or Probifor 5-7 days

Diabetes mellitus in a child - long-term administration up to 6 weeks and repeated courses with any probiotics of different generations are recommended.

Prevention of infectious diseases in children - 2-3 times during the year to conduct seasonal courses - Beefilis, Bifidumbacterin Forte.

The adjustment of intestinal dysbiosis with probiotics is made taking into account its severity (1-3 degrees). In clinical practice, when choosing a probiotic for the treatment of children, the following rules are recommended:

With a lack of lactobacilli in the analysis for dysbacteriosis, it is not necessary to prescribe lactobacilli. When correcting dysbiosis, preference is always given to bifidobacteria-containing drugs, since the basis of the microflora of the large intestine is bifidobacteria and they restore such disorders. Monopreparations containing only 1 type of bacteria Lactobactrin and Bifidumbacterin are indicated only for milder forms of intestinal infections and 1 degree of dysbacteriosis. With 2–3 degrees of dysbacteriosis, 3rd and 4th generation drugs are recommended — Probifor, Bifiform, Bifidumbacterin Forte. In severe colitis, infectious ecutrocolitis, Probifor is indicated; a simultaneous use of Enterol + Bifilis or large doses of Bifidumbacterin Forte may be an alternative. Probiotics for children with lactobacilli are best used in conjunction with bifidobacteria, which suppress diaphoretic microorganisms and protect the mucous membrane of the colon. With ulcerative lesions of the stomach and duodenum, with acute gastroenteritis of infectious etiology, with a deficiency of lactobacillus in the proximal gastrointestinal tract, lactic probiotics are prescribed - Gastrofarm, Atsipol, Lactobacterin, Acilact, Biobacton, Linex.Colibic probiotics - the list of these drugs Bioflor, Kolibakterin, Bifikol for the treatment of children are used with caution, only according to strict indications. The duration of probiotic therapy of the 1st generation is 4 weeks, the 2nd generation takes 5-10 days, further taking lactobacilli and bifidobacteria, 3-4 generations no more than 5-7 days with acute food intoxication and intestinal infections. If taking drugs from the list of probiotics does not lead to an effect, it is necessary to change the tactics of treatment, it is possible to prebiotics, antifungal drugs in tablets, intestinal antiseptics, bacteriophages.

Researchers have shown that the use of probiotics with other pathologies of extra-intestinal localization also shows the effect of therapy, since probiotics have the property of improving metabolism and immunomodulatory effects.

Dysbacteriosis - a problem of many people, invisible from the outside, but bringing strong discomfort and making serious changes in the usual life. Funds eliminating dysbacteriosis are advertised everywhere, but in order to choose the very medicine that will really help eliminate this disease, it is necessary to understand their varieties and properties.

Tablets for dysbiosis

Tablets for the treatment of dysbacteriosis can be divided into two main groups - antibacterial (eliminate the main cause of the disease - pathogenic microorganisms) and probiotic (contribute to the reproduction of the intestinal flora, increase immunity).

The cause of dysbiosis can be Escherichia coli, entorococcal, staphylococcal, candidomycosis and other infections. The common drugs used in drug treatment are Levomycetinum, Streptomycin, Nystatin, Intetrix, Pyfamucin, Furazolin, and Enteroseptol.

The doctor can prescribe drugs for the treatment of dysbacteriosis only after bacterial seeding and determining the sensitivity of the causative agent to the chosen remedy.

Drugs that increase immunity, normalize the microflora and eliminate the negative symptoms of dysbiosis:

Sorbents. Polypefan, activated carbon, Pepidol - sorbent preparations that bind toxic substances and prevent the spread of putrefactive processes in the intestine. Used in the first stage of treatment of dysbiosis.

BS from live strains. Bifikol, Baktusubtil, Enterol, Kolibakterin – are used in the first and second stages of dysbacteriosis, made on the basis of microorganisms that form normal intestinal flora.

Prebiotics. Dufalak, Normaz, Khilak-Forte belong to the group of prebiotics, which do not contain strains of microorganisms, but create favorable conditions for the development of beneficial microorganisms, can be used at any stage of treatment of dysbacteriosis.

Probiotics. Bifidumbacterin, Linex, Narine, Lactobacterin, Bifiform - probiotics, which represent an extensive group of agents used to treat dysbacteriosis of any stage. They contain live strains of beneficial bacteria that normalize the intestinal microflora and inhibit pathological microorganisms.

Enzymes Mezim-Forte, Polizim, Digestal, Panzinorm-Forte belong to the group of enzymes that require the normalization of digestive processes, the digestion of food and the absorption of beneficial components in the stomach and intestines.

Immunomodulators Levomizol, Dekaris relate to immunomodulators, contribute to the normalization of the local immunity of the gastrointestinal tract, are used in the final stages of treatment to consolidate positive results.

Motor function reducers. Duspalatin, Trimedat, Meteospazmil, Immudon - these drugs restore normal intestinal motility, which helps to eliminate symptoms such as diarrhea, bloating, flatulence.

Stimulants of the intestinal epithelium.Essentiale and other drugs that stimulate intestinal epithelial cells help to get rid of intestinal colic.

7 best drugs for dysbiosis

The appearance of a wide variety of dysbacteriosis remedies is due to different criteria for evaluating their effectiveness, which makes it difficult to find one best medicine.

Consider several well-known drugs for these criteria:

Lactobacterin is available in the form of tablets and powder - it does not have a capsule shell, it is not used for candidiasis or hypersensitivity, allergic reactions are possible as a side effect, can be taken together with an antibiotic, there are no contraindications for pregnant women, be sure to be refrigerated.

Acylact (suspension, pills), is contraindicated in candidiasis, allergy to the drug is possible, simultaneous administration with antibiotics is allowed, pregnant women are prescribed by a doctor, contraindicated to children under 3 years old, stored in the refrigerator for up to 12 months.

BioBacton - in capsules is not produced, it is prohibited in case of candidiasis, there is a possibility of an allergic reaction, it is compatible with antibiotics, suitable for children, stored in the refrigerator.

BifidumBacterin is a powder and solution in ampoules, canceled if hypersensitivity or candidiasis is detected, incompatible with antibiotics, children are prescribed from the age of 3, pregnant and lactating mothers are indicated only, and are stored in the refrigerator.

Probifor - without a capsular shell, without contraindications, without side effects, compatible with antibiotics, it is possible to regularly use the product during pregnancy and lactation, suitable for children over six months, stored in the refrigerator.

Hilak forte - capsular shells do not, as well as contraindications and side effects, can be taken with antibiotics, during pregnancy and during the lactation period, universal for any age, stored at a temperature of less than 10 degrees.

Linex - is available in a capsule shell, has no contraindications and no side effects, can act in parallel with antibiotics, without age restrictions, can be stored in a dry room with an air temperature of not more than 25 degrees.

Lactic acid bacterial probiotics

There are tablets and powder form of drugs in this group. The first is Lactobacterin, the second is Biobacton and Acilact. Acylact is also available in the form of suppositories, which is considered safer to use, since it does not inhibit beneficial microorganisms that live in the intestines. The above remedies can be taken together with antibacterial drugs, but they are not suitable as the only means of treating complex dysbacteriosis, as they are monodrugs, that is, contain a therapeutic substance of the same type.

Bifidobacteria based probiotics

Probiotic preparations based on bifidobacteria have various forms of release and are among the very first means of treating dysbacteriosis. So, they distinguish the tablet form (Bifidobacterin Forte) and the powder form (Probifor) of drugs. There are contraindications for the use of suppositories and tablets with bifodobakterijami children younger than three years old, also drugs in this group are not combined with antibiotics.

Probiotics - a combination of bifidobacteria and lactobacilli

This type includes powdered probiotic Florin Forte, suitable for children from infancy and adults. For infants the drug is mixed in the proportions indicated by the doctor with the formula for feeding or breast milk, older children and adults take the drug with food. Florin Forte requires special storage conditions that are easily observed in the refrigerator: 0 - 10 degrees.Some antibiotics can worsen or change the work of Florin, therefore, for the simultaneous use of these drugs, you should consult a doctor who will help you choose an effective combination of drugs.

Analogue of Florin Forte on the composition of the bacteria is Linex.

Compared with the first drug, it has undeniable advantages:

Additional enterococcus in the composition of the drug enhances the complex effect,

No special requirements for storage conditions

Easily combined with other antibiotics,

It has no contraindications for use by pregnant and nursing mothers.

It has no contraindications for age - babies do not have to mix the agent in milk, but you can simply dissolve the contents of the capsule in warm water.

Probiotics with bifidobacteria and lactobacilli can be dangerous for immunocompromised patients or excessive allergic sensitivity. If you have these health defects, you need to consult a doctor for correct dose calculation and the ability to take probiotics.

Bifidobacteria based probiotics in combination with other bacteria

An interesting combination is the drug Bifikol, which contains, in addition to the standard set of bifidobacteria, conditionally pathogenic E. coli, which is also normally found in the intestinal microflora and is able to suppress microbes with greater pathogenicity. Unfortunately, the simultaneous reception of a course of antibiotics and Bifikola can be harmful to the body, which can not be said about its analogue Bifiform with enterococci.

Lactulose-based prebiotics

It is known that simple, quickly digestible carbohydrates are the main resource for the development of pathogenic intestinal microflora. Lactulose prebiotics contain a special enzyme that breaks down carbohydrates to organic acids, which inhibit the development of microbes and reduce pressure.

Known drugs from this group:

Preparations of prebiotic composition

To maintain and restore the balance of intestinal microflora invented drugs with a light acid and fatty acids, which contribute to the regeneration of natural microflora. Hilak Forte, for example, helps to strictly observe the balance of electrolytes and restore epithelial cells of the intestinal mucosa. Lactobacteria in its composition emit lactic acid, which regulates acidity, favorable for the development of beneficial microflora.

Candles for dysbiosis

Drug treatment of dysbacteriosis is carried out not only drugs in the form of capsules and tablets, but also in the form of suppositories, which differ in composition (antibiotics, probiotics) and method of use (vaginal, rectal). The advantages of this dosage form of funds include local exposure, which allows you to normalize the microflora locally, without affecting the entire body in general.

Vaginal suppositories are used to treat bacterial vaginosis in women, and to restore normal vaginal microflora.

Polygynax, Terzhinan, Betadine - antibacterial suppressors inhibit the development of pathogenic microorganisms (bacteria and fungi), prevent trichomoniasis and other infections. A contraindication for use is pregnancy, especially in the later periods.

Labilakt, Atsilakt, Vagilact, Ginoflor - candles with a probiotic complex, which make up lactobacteria, bifidobacteria, as well as estriol, lactose and other ingredients. These drugs restore the normal microflora of the vagina after treatment with antibiotics, with excessive reproduction of pathogenic microorganisms due to hormonal imbalance, with a weakened immune system, diabetes mellitus and thrush.

Rectal suppositories restore the normal intestinal microflora in adults and children, there are two groups of agents - antibacterial and probiotic.

Apis, Kipferon, Prostotopin, Anuzol, Nilegan, Genferon, Levomycetin, Procto, Viferon - antibacterial, antimycotic rectal suppositories contain local antibiotics, antiviral and antifungal agents, they may include glucocorticosteroids, which prevents inflammation of the intestinal walls. The local method of using suppositories eliminates the side effects, while maintaining maximum effectiveness of the drug for dysbacteriosis of any complexity. However, rectal antibacterial suppositories cannot be used during pregnancy.

Bifinorm, Lactonorm, Lactobacterin, Bifidumbacterin - candles with a probiotic complex that supply the intestines with beneficial microorganisms, restoring its normal microflora. The use of probiotics in the form of suppositories is more effective than in the form of tablets or capsules, since lacto-and bifidobacteria are not destroyed during the passage of the gastrointestinal tract, and are immediately delivered to their habitat.

Ortobrebio - the best bad from dysbacteriosis

Among dietary supplements to improve intestinal health in dysbacteriosis, the prebiotic OrthoPrebio gives the best results. Its effectiveness is explained by the uniqueness of the main ingredient of the drug - inulin-rich in oligofructose. This inulin is an original patented product that is produced in Belgium under the trade name "Raftilose Synergy1".

Among the unique properties of this drug:

Protection of the large intestine over the entire length,

Not able to cause an allergic reaction, as sometimes happens with milk-based prebiotics,

Not absorbed through the intestinal mucosa, therefore - does not penetrate into the bloodstream and does not require filtration and excretion by the kidneys,

Works in conjunction with Fibregum acacia resin, produced in France by ColloidesNaturelsInternational,

Pleasant to use because of the sweet taste that gives oligofructose.

A detailed study of the properties of the complex drug inulin and oligofructose is devoted to a multitude of studies by international scientists from leading scientific institutions in the most developed countries. The formula Synergy1 is intensively applied in the pharmaceutical industry of Japan, the European Union, the USA and more than 50 countries.

The practice of using OrthoPrebio shows that natural plant-inulin with oligofructose works several times more efficiently than similar preparations with lower-quality ingredients.

What is the intestinal microflora

Many processes in the human body are regulated by beneficial bacteria. They help to digest food and absorb nutrients from it, support the immune system and participate in metabolism. With the help of these microorganisms, most vitamins are produced that are necessary for human life. They are located in the intestine, which is often also a haven for pathogenic bacteria. The balance between microorganisms in the human body is called microflora. If it is broken, good bacteria can not cope with their work? and various health problems arise. Then the person is acutely faced with the question: intestinal microflora - recovery. Preparations for this exist different, but first you need to understand the causes of this condition, which is called dysbacteriosis.

Why intestinal microflora is disturbed

Most often this happens for such reasons:

  • because of taking certain medications, especially antibiotics, which destroy any bacteria, even beneficial ones,
  • due to unhealthy diet, non-compliance with the regime of eating, fascination with junk food and snacks on the go,
  • due to reduced immunity, especially against the background of infectious and inflammatory diseases or chronic diseases,
  • from disorders of the gastrointestinal tract due to surgery, poisoning or diseases: gastritis, ulcers and others,
  • stresses, lack of exercise and bad habits can also cause a disturbance in the intestinal microflora.

What symptoms does this condition cause?

In violation of the intestinal microflora are most often noted:

  • upset stool - constipation or diarrhea,
  • flatulence, heartburn, bloating, increased flatulence,
  • stomach ache,
  • smell from the mouth,
  • loss of appetite, deterioration of performance,
  • reduced immunity
  • in advanced cases there is a violation of the heart rhythm and deviation in the work of other organs.

Intestinal microflora: recovery

Preparations containing live bacteria and the environment for their reproduction, are the most common means of treating this disease. But they should be prescribed by a doctor, since complex therapy gives a greater effect. There are drugs in the form of tablets or capsules, syrup or powder for suspension. But it is believed that when passing through the stomach of the microorganisms die, so it is more effective to use such funds in the form of microclysmus or candles.

You can use folk remedies to restore microflora. For example, a mixture of dried apricots and prunes with honey, decoctions or extracts of Hypericum, calendula, yarrow, eucalyptus or plantain. It is useful to eat berries of a cowberry, garlic and grated sour apples.

A mandatory stage of treatment should be good nutrition, excluding fatty, spicy and canned food, fast food and soda. It is very useful for intestinal microflora to use dairy products. And they must be natural, and they need to drink at least half a liter a day.

In some cases, antibacterial drugs can be used to destroy highly propagated pathogenic microflora: Penicillin, Tetracycline, Cefalosporin, or Metronidazole. But probiotics are surely taken along with them.

Types of drugs for the treatment of dysbiosis

1. Probiotics are medicines that contain live bifidobacteria or lactobacilli. They can be a monodrug, as part of which only one bacterium or a complex means for colonizing the intestines with all beneficial microorganisms. These include "Linex", "Bifidumbakterin", "Atsipol" and others.

2. There are also medicines that help the body produce its own prebiotic bacteria. Most often they contain lactulose, which is a breeding ground for them. These are “Lactusan”, “Normazet”, “Duphalac” and others.

3. But the most effective drugs for restoring intestinal microflora are symbiotics. They contain both live bacteria and substances for their growth. These include "Biovestin Lacto", "Bifidobak" and others.

List of the most famous drugs

In recent years, one of the most popular was the query: "Intestinal microflora - recovery." There are various and effective drugs for this, but they should be taken only on the recommendation of a doctor. Which ones are the most common?

1. Monocomponent probiotics:

2. Multicomponent probiotics:

Characteristics of probiotics

These are the most popular preparations for the restoration of intestinal microflora. The list of probiotics is long, but they all have their own characteristics. Therefore, it is better to choose a medicine after consulting a doctor. Probiotics are natural remedies and contain bacteria that exist in the human intestine. These medicines are safe and do not cause any side effects. They are used for complex treatment of chronic and infectious diseases of the gastrointestinal tract and in those cases when it is necessary to restore the intestinal microflora after antibiotics. Drugs in this group can be divided into three types:

- Drugs containing bifidobacteria: "Bifidumbacterin", "Bifiform" and others. These microorganisms are the most common in the human intestine. They are able to inhibit the activity of pathogenic bacteria. Therefore, these drugs are effective for salmonellosis, dysentery, allergic diseases.

- Preparations with live lactobacilli: "Lactobacterin", "Biobacton", "Atsilakt" and others. They are well used during antibiotic treatment to protect the intestinal microflora. But since they contain only one type of microorganisms, they do not help against complex dysbiosis.

- Polycomponent funds: Linex, Atsipol, Bifiliz, Florin Forte, Bifikol and others. They contain additives that enhance the action of bacteria.

The best lactulose-based drugs

The effect of such drugs is based on the property of this substance to be broken down in the intestine into low molecular weight organic acids. They inhibit the activity of pathogenic microorganisms, and these enable beneficial bacteria to grow normally. Lactulose contain "Duphalac", "Portalak", "Normaze" and some others. They almost do not cause side effects, but there are still some restrictions on their use. It is not recommended to use such drugs to patients with diabetes mellitus, those who have lactose intolerance or intestinal bleeding.

Comprehensive Medicines

Many believe that the best preparation for restoring intestinal microflora is Hilak Forte. In addition to lactobacilli, it contains lactic and other organic acids, which have a positive effect on damaged epithelium cells. They also restore acidity in the gastrointestinal tract. These drops can be applied at any age, they are well tolerated and effectively relieve the symptoms of dysbiosis: abdominal pain, flatulence and upset stool. Laminolact is also a popular drug. It comes in the form of delicious dragees. Their composition includes, in addition to beneficial bacteria, vegetable protein, oats and sea kale, which serve as a nutrient medium for the growth of microorganisms.

Restoration of microflora in children

In a child, the intestines are completely colonized by beneficial bacteria only by the age of 11. Therefore, they are much more common dysbacteriosis. Stress, unfamiliar food, infectious diseases - all this causes the death of beneficial microorganisms and the reproduction of pathogens. Especially often requires the restoration of intestinal microflora after antibiotics. Preparations for children are not all suitable, so only a doctor should prescribe treatment. And a child who feeds on breast milk is not recommended to be treated at all for dysbiosis. The main thing is for mom to eat properly and not give the baby any more food. But in difficult cases and with artificial feeding, special preparations are still needed to restore the intestinal microflora. Not all of them are suitable for children:

- “Linex” in the form of powder can be given to babies from birth. It is added to water or breast milk. But the drug contains lactose, so it can not be given to everyone.

“Primadophilus” is also a powder diluted in any liquid. Only it is necessary to observe the dosage recommended by the doctor.

- The drug "Hilak Forte" is available in drops. Its peculiarity is that it is incompatible with dairy products.

- “Bifidumbakterin” is taken with meals. This drug in powder form can also be dissolved in any liquid.

If a child suffers from colic, disorders of the stool and abdominal distention, does not gain weight well and often cries, he must definitely restore the intestinal microflora.

Preparations: reviews of the most common

Recently, a violation of intestinal microflora is increasingly common. And not all patients go to a doctor about this.Taking drugs on the advice of friends or pharmacists, they often do not get the desired result. But there are also such means that everyone likes, and doctors prescribe them most often. These are Hilak Forte and Linex. They have no contraindications and are well tolerated. It is convenient to drink these drugs, especially the capsules of Linex. And many like the sour taste of Hilaka Forte. What drugs to restore the intestinal microflora are not very satisfied with the patients? These are mainly those that need to be stored in a refrigerator and diluted with water. This is rather inconvenient, although this form is more acceptable for small children. But in any case, you need to take medicines only on prescription.

What is the significance of lactobacilli and bifidobacteria for the intestines? A healthy climate in the intestines affects the state of the whole human body. Lacto-and bifidobacteria strengthen and restore the intestinal microflora. Today the release of such funds is diverse. For effective treatment and prevention it is important to choose the right means.

The value of live bacteria for the intestines

Live bacteria are important components of a healthy intestine. They regulate the work of the gastrointestinal tract, as they participate in the process of digesting food. Beneficial bacteria break down fiber, are involved in the hydrolysis of proteins, neutralize fatty acids. They also promote the synthesis and assimilation of vitamins, neutralize toxic substances, prevent the reproduction of pathogenic bacteria.

Causes and consequences of the lack of beneficial intestinal microorganisms

If the intestinal microflora is out of balance, the beneficial microorganisms become smaller. The number of pathogenic bacteria, on the contrary, increases. As a result, the functioning of the gastrointestinal tract deteriorates, which immediately affects the state of other organs and systems. Deficiency of beneficial bacteria usually occurs for the following reasons:

  • long-term antibiotic therapy,
  • infectious diseases,
  • mental and physical overload
  • poor quality food.

Against the background of deficiency of beneficial microorganisms, a condition known as dysbacteriosis develops. It is accompanied by symptoms such as bloating, pain in the stomach and intestines, nausea, changes in stool, and deterioration of health. In this case, the recommended treatment with drugs with bifidobacteria or lactobacilli.

Further, the difference between these probiotics will be discussed, and in what cases each of them should be used.

What is the difference between bifidobacteria and lactobacilli?

Bifidobacteria belong to the group of anaerobic gram-positive microorganisms and “live” in the large intestine. In breastfed babies, they make up to 90% of the microflora. In adults, the concentration of bifidobacteria is reduced by an order of magnitude, which does not prevent them from performing their basic functions. The first is the synthesis of organic acids and vitamins of group B, the neutralization of toxins, the suppression of the growth of pathogenic microflora.

Lactobacilli are optional anaerobic gram-positive microorganisms. They are located in the intestine, vagina, mouth and most parts of the gastrointestinal tract. The main task of lactobacilli is to produce lactic acid, without which normal digestion is impossible. In addition, lactic acid blocks the reproduction of pathogenic fungi and bacteria.

Popular Lactobacillus Drugs

Preparations with lactobacilli are available in the form of tablets, suppositories, capsules and powder for the preparation of suspensions. One of the most famous medicines are probiotics "Acilact", "Acipol" and "Lactobacterin". They stabilize the intestinal microflora and eliminate the effects of a shortage of lactobacilli.

Lactobacillus functions

  • They prevent the growth of pathogenic microorganisms.Lactobacilli synthesize organic acids, maintain an acidic environment in the intestines, produce hydrogen peroxide, antibiotic-like substances, thereby preventing the dispersal and multiplication of infection.
  • Strengthen immunity. Since they, being alien organisms, come into contact with the epithelium of the intestinal wall, they stimulate the defense mechanisms. Lactobacilli and other parietal microflora accelerate the synthesis of antibodies, lysozyme, interferons, cytokines and activate phagocytosis.
  • Participate in membrane digestion. Lactobacilli produce enzymes that break down milk sugar and prevent the occurrence of lactase deficiency. Without these microorganisms, milk is not normally digested.
  • Contribute to the metabolism of bile acids. Under the influence of lacto-and bifidobacteria in the distal colon, the bile acids transform and stimulate the secretion of water into the intestinal lumen. This prevents dehydration of feces (hard stools are poorly removed from the body, damage the intestinal mucosa, are one of the causes of an anal fissure and other pathologies).
  • Thanks to the microflora, cholesterol hydrolysis occurs in the large intestine, and toxins and nutrients are undigested in the small intestine.
  • Participate in the detoxifying function of the intestine. They help to reduce the permeability of vascular and tissue barriers to toxins and pathogenic microorganisms.
  • In the process of vital activity, lactobacilli produce gases, acids, thereby activating intestinal peristalsis.


Lactobacilli, along with other members of the normal intestinal microflora (Escherichia, bifidobacteria, eubacteria), are involved in the synthesis and absorption of vitamins K, B, E, PP.

Reducing the number of normal microflora contributes to indigestion, the development of infectious diseases, weakening of the immune system, the occurrence of pathologies of the gastrointestinal tract.

Sources of lactobacilli

Medicines containing live cultures of microorganisms - probiotics. They are prescribed for the prevention and correction of dysbiosis, treatment of intestinal infections, inflammatory bowel disease, diarrhea and constipation.

There are drugs that contain only lactobacilli, and there are complex ones (they also include other representatives of the intestinal microflora). The composition of some drugs include vitamins and minerals.

Medicines containing lactobacilli:

  • Laktomin,
  • Spazmolak,
  • Probiovit,
  • Probiologist,
  • Lactobacterin,
  • Acylact,
  • Atsipol
  • Gastrofarm
  • Linex,
  • Yogurt,
  • Lactobacterin-Biopharma,
  • Laktomun,
  • Lacidofil,
  • Lacto G,
  • Laktovit Forte,
  • Multiprobiotic Simbiter Acidophilic.

Drugs should be taken with meals. Those drugs that are sold in powder form are diluted in water (not hot). It is strictly not recommended to dilute them with alcoholic beverages.

Lactic preparations may be contraindicated in:

  • with marked candidosis,
  • to patients with catheters in the central vein,
  • after operations on the gastrointestinal tract, the heart, in the mouth,
  • sick in a state of danger to life
  • if there is blood in the feces,
  • children up to 3 years with short bowel syndrome.

Therefore, self-treatment is not recommended. Before use, consult a gastroenterologist. Especially if these drugs are prescribed to newborns.

Raw materials for the manufacture of food are milk mixtures. They are fermented with kefir starter and add bifidobacteria and lactobacilli. The stores sell kefir, yogurt and other dairy products, in the names of which there is a prefix:

It is understood that they contain live cultures of bifidobacteria and lactobacilli.

If fermented milk products have been pasteurized, they cannot contain the necessary microorganisms, since these cultures are very sensitive to temperature.

Sources of lactobacilli are hard cheeses:

1 g of cheese contains 10 7 –10 9 CFU of bifidobacteria and lactobacilli.

Yogurts and kefirs containing lactobacilli:

In addition to products with lacto-and bifidobacteria to restore normal microflora, it is necessary to use and substances that promote the growth of these crops:

  • lactulose,
  • polyunsaturated fatty acids (fish and vegetable fats),
  • lysozyme

Systematic consumption of fermented milk products, enriched with bifidobacteria and lactic acid bacteria, has a beneficial effect on the microflora. But the content of these crops in products is low. And with some diseases of the digestive system, they are contraindicated. Then for the treatment of dysbiosis and intestinal infections recommend drugs with lactobacilli. Some of them are recommended to take even the newborn.

Lactobacilli for children and newborns

Most of the drugs with lactobacilli are available in capsule form. Small children are not able to swallow them. Special water soluble powders have been created for them, which are added to food (it should not be hot, since microorganisms will die). If the doctor prescribed the drug in a capsule, it is not terrible - it opens up, and the contents are mixed with food.

Starting from the neonatal period, for the prevention and treatment of dysbacteriosis, gastroenteritis, in the complex therapy of allergic diseases are prescribed:

  • Yogurt,
  • Lactobacterin dry,
  • Acylact is dry,
  • Atsipol
  • Linex,
  • Laktomun,
  • Lacto-g.

These drugs are prescribed and adults, only in large doses. A Multiprobiotic Simbiter Acidophilous is recommended for children under 3 years old (it is not prescribed for adults).

It is absolutely not recommended to prescribe drugs independently, especially for children, even if the instructions do not indicate side effects. It must be remembered that individual intolerance to the drug may occur.

Can I take lactobacillus drugs for prevention?

The instructions for the drugs says that they are used not only for treatment, but also for prevention. This does not mean that they should be accepted by everyone. Assign them if there are prerequisites for the development of pathology:

  • medication (antibiotics, glucocorticosteroids, cytostatics, antisecretory agents),
  • dysfunction, resection of ileocecal valve,
  • inflammatory bowel disease,
  • enzymopathies
  • intestinal absorption disorders.

Lactobacillus should be taken and those who are contraindicated dairy products. If there are no contraindications, then prophylaxis should be carried out with nutrition correction. Add to diet:

  • yogurt,
  • cottage cheese,
  • sour cream
  • hard cheeses
  • kefir and yogurt (containing live cultures).

A pill is better to drink when there are certain indications and revealed a clear deficiency of lactobacilli. For this there are special research methods.

Diagnostics and content standards

Carry out the determination of the number of lactobacilli in suspected dysbiosis. To do this, investigate:

  • the contents of the small intestine
  • feces

In the contents of the small intestine, the number of microorganisms is 10 4 –10 8 CFU per 1 g of intestinal contents. This is a collection of all representatives of the normal intestinal microflora (enterobacteria, streptococci, staphylococci, lactobacilli, fungi, clostridia, bifidobacteria). Of these, 85–90% should be bifidobacteria and lactobacilli.

Normal content of lactobacilli in feces:

What are lactobacilli and what are they for?

Microorganisms of this group are located in the entire digestive tract - from the mouth to the colon. Such bacilli can survive even in the most aggressive environments, such as gastric juice. One of the functions of bacteria in this group is to help form the general and local level of immunity resistance. Since microorganisms have the property of immunomodulation and the formation of interferon.

With the presence of lactobacilli in the body, the process of lactic acid production begins, which is necessary for the suppression of harmful microbes. The level of beneficial bacteria is significantly reduced when suffering stressful situations, depressive states and taking drugs from the group of antibacterial. All of these factors also adversely affect the intestines and immune protection.

A deficiency of nutrients in the gastrointestinal tract can lead to the occurrence of flatulence, constipation and a violation of the chair. The elements of this family have antitumor properties, protect the body against diseases and infections.

What are bifidobacteria and what they do

This group is the largest in comparison with other elements in the gastrointestinal tract - about 90% of the total. They are in the human body throughout life. Such microbes can not provoke the occurrence of diseases. On the contrary, they interfere with the process of reproduction of various pathogens.

The largest accumulation of such bacteria is in the colon, forming its parietal microflora. They are engaged in the production of vitamins B, amino acids and proteins that stimulate the absorption of nutrients.

Types and benefits of bifidobacteria and lactobacilli

The group of bifidobacteria In This is the basis of the process of microbiocenosis occurring in the colon. They make up more than 90% of the positive flora, act as a regulator of the gastrointestinal environment, oral cavity, respiratory tract, urinary tract. They participate in the formation of biofilm, increase the protective properties of the mucous membrane, and also create a barrier against the penetration of toxins.

The action of this group occurs on three levels:

  • The walls of the mucous membranes.
  • The lumen of the intestinal system.
  • The level of immune protection.

Have a positive impact on the work of the kidneys. In comparison with lactobacilli, they are more active when they participate in the metabolism of carbohydrates, normalize blood sugar levels. Take part in the mineral metabolism, contribute to a better absorption of calcium, iron. Increase the level of natural killers four times. Reduce the level of permeability of the mucous walls. That minimizes the number of allergens, toxins and slags.

Due to an important role in creating a balance of microflora, these bacteria improve the skin condition, increase immunity, fill the body with strength and energy.

Lactobacillus group L present in the oral cavity, respiratory tract, small intestine, urogenital system. In the female body, such trace elements form 90% of the microflora of the vagina.

Impact on three levels:

  • The walls of the mucous membranes.
  • Internal lumen of the intestine.
  • The level of immune protection.

Positively affect the degree of general and local protection of the body. Act as an immunomodulator. In comparison with bifidolactobacteria, they more intensively protect the body from ENT diseases, lung diseases, skin ailments. Effective with diseases of gynecology. Able to destroy bacteria that cause ulcers and gastritis.

Microorganisms are a barrier to the occurrence and spread of viral and genital infections, influenza, ARVI and hepatitis. Participate in lipid metabolism - control and normalize cholesterol levels, reduce the risk of heart attack and stroke.

When searching for the answer to the question which is better than bifidobacteria or lactobacilli, one group cannot be distinguished. For the body it is important to obtain both types of microorganisms. In symbiosis, they are able to normalize the intestinal flora, stimulate the proper functioning of the gastrointestinal tract, increase immunity, reduce the risk of viral infections and allergic reactions.

Deficiency of lacto-and bifidobacteria

With an insufficient amount of these groups of substances in the body, the microflora balance is disturbed. That is, the number of pathogens exceeds the number of good bacteria.For the right balance, the ratio of "pests" and "helpers" should be one to one hundred. In another ratio, where the harmful substances outweigh the useful ones, all the systems of internal organs suffer. The deterioration is due to the fact that a healthy microflora is important for many processes occurring in the gastrointestinal tract.

These processes include:

  • Enzymatic digestion of food - protein hydrolysis, the breakdown of fiber, the fermentation of carbohydrates, the neutralization of fatty acids.
  • The formation in the intestine of an acidic environment is the prevention of reproduction of pathogens.
  • Absorption and synthesis of vitamins and other nutrients.
  • Protection of the body against the accumulation of toxins and slags.
  • Strengthen immune protection.
  • Participation in the metabolism of bile acid and cholesterol.

In the absence of the proper amount of beneficial bacteria, all the above processes are violated, which can lead to the emergence of a disease such as dysbacteriosis. In order not to become hostage to the deficit of "good" microorganisms, one should know what can cause an imbalance.

What harms the microflora:

  • Uncontrolled intake of antibiotics.
  • Lack of balanced nutrition.
  • Eating junk food - fast food, convenience foods, carbonated drinks.
  • Excessive drinking and smoking.
  • Bad environmental situation.
  • Frequent transfer of stressful situations and depression.

To restore the microflora - raising the level of bacteria and lacto and bifido on the shelves of pharmacies presents a large number of funds. You can also fill the deficit with the help of individual foods.

Preparations for the restoration of microflora

Medicinal products containing beneficial bacteria belong to the group of probiotics. Currently, pharmacological companies have developed a wide range of drug release forms. They act as an assistant in the process of restoring the natural environment in the intestines. May be a drug or dietary supplement. Aimed at combating pathogens and treating diseases caused by deficiency.

Forms of release

Capsules and candles. They have a capsule shell that protects bacteria from gastric juice and the external environment. Therefore, they can not be stored in the refrigerator. The highest level of efficacy is achieved when used together with antibacterial drugs. Most of the funds can be taken regardless of the meal. Candles are used for the imbalance of microflora in the vagina.

Dry powder products. Often contain only one group of probiotics. When taken together with antibacterial substances, the effectiveness of the powder is reduced. The individual components of the composition can be destroyed under the influence of the juices of the stomach. Often the medication depends on the time of consumption of food. Due to the lack of containment, they should be stored at sub-zero temperatures.

Liquid form preparations. Taking this type of medication must be half an hour before meals. The tool is ready to receive - it does not need to be further diluted with water. May be used in combination with antibiotics. Substances are stored only at sub-zero temperatures. Under the influence of gastric juice is the splitting of some microorganisms.

Foods with beneficial bacteria

To restore the balance of bifidobacteria and lactobacilli in addition to the use of drugs, it will be useful to use suitable food. A large amount of fermented milk products contains essential trace elements. Among them are sour cream, kefir, natural yoghurt without additives, cottage cheese. The label of most of these products contains information on the presence of certain strains of beneficial bacteria.

Reception of products and preparations containing microorganisms of groups B and L will help restore the balance of flora in the intestine, reduce the accumulation of toxins and toxins in the body, normalize the digestive tract and improve the immune system. And the observance of proper diet, rejection of bad habits and minimization of stress contribute to the natural process of production of lactobacilli and bifidobacteria.

What are probiotics?

Probiotic is a living microorganism that makes up the human gut normofolor. These drugs are non-pathogenic yeast bacteria that have resistance to conditionally pathogenic or pathogenic microorganisms, which are designed to perform many different beneficial functions in the gastrointestinal tract, produce biotin, vitamin K, folic acid.

Probiotics help restore the normal microflora of the mucous membranes of the gastrointestinal tract, strengthen the immune system and protect it from the effects of harmful toxic substances.

That is why a change in the balance of microflora in the intestines, dysbiosis can lead to serious diseases. Clinical syndromes such as antibiotic-associated diarrhea, dysbiosis, and also SARS and influenza require treatment with probiotics, Linex analogues.

Types of probiotics for children and adults

We can say that probiotics for the intestinal list are quite large, but we will tell only about some of them. Currently, there are several different types of drugs that normalize the intestinal microflora.

  1. first-generation drugs based on one type of beneficial bacteria - Bifidobacterin, Lactobacterin, Colibacterin,
  2. the associated version of dietary supplements - Linex,
  3. third-generation drugs on a combined basis - Bifiliz, Atsilakt, Bifiform,
  4. metabolic probiotics - Hilak forte,
  5. drugs of the second generation containing antagonistic bacteria - Baktisubtil, Biosporin, Sporobakterin.

For the normal functioning of the intestine, it is necessary to take not only live bacteria, but also prebiotics, which are undigested food elements that have a stimulating effect on certain types of microorganisms and bacteria in the colon.

Natural prebiotics contain high-molecular-weight carbohydrates, which become an excellent selective material that uses lactobacilli and colon bifidobacteria.

Lactobacilli for the intestinal preparations are most effective for serious problems with microflora. Especially with dysbacteriosis.

The most popular live bacteria for intestinal drugs:

  1. Bifidumbacterin forte is the probiotic of the last generation. It has such a strong shell that the capsule easily overcomes the stomach and small intestine and enters the large intestine intact.
  2. Profibor is a more concentrated drug with bifidobacteria. One of its bag contains about 10 servings of trace elements.
  3. Biovestin It contains two different types of bifidobacteria and is produced in liquid form.
  4. Linex is one of the most effective probiotics, which is distributed throughout the territory of the Russian Federation. This is an inexpensive and affordable drug that contains a complex of microflora components that are located in different parts of the large intestine.
  5. Bifiform - It is also an inexpensive, effective and affordable product in which, along with the good bacteria, there are also enterococci, which help to completely colonize all parts of the large intestine with beneficial microorganisms for certain diseases. Treatment with this drug is prescribed by a gastroenterologist.

Probiotics such as Probalans, which is a dietary fiber, Duphalac - helps to increase the level of acidity in the intestines and others.

It must be remembered that, depending on the type of disease, a gastroenterologist prescribes certain medications.

For example, if a person has constipation, then probiotics are prescribed as adjuvants that compensate for the lack of beneficial bacteria that are necessary to restore the intestinal microflora.

It is also impossible to underestimate the beneficial properties of lactobacilli and bifidobacteria, which, as a result of their vital activity, form substances that positively affect the entire process of the stomach and large intestine, and are involved in the normalization of its motility.

Thus, with the help of probiotics, the problem of irritable bowel and constipation, even chronic, are resolved very quickly. The most important thing is that the body receives in time a natural preparation necessary for it or bacteria along with food in order to avoid the development of various intestinal diseases. Also, antibiotics that a person takes during a period of various diseases have a negative effect on the intestines, killing all good bacteria and disrupting its microflora. Their shortage must be compensated for by various probiotic preparations, which will be able to resume normal gastrointestinal function as soon as possible.

For the past 40 years in a row in medicine they use the cheapest kind of lactic probiotics - lactulose, which is able to solve a large number of different problems with the intestines. This substance passes absolutely through all parts of the gastrointestinal tract, remaining the perfect environment necessary for the development of beneficial bacteria and microorganisms in the large intestine in order for it to properly perform its function. You can buy such a drug and others at a regular pharmacy at affordable prices. Also, some foods contain a large number of beneficial bacteria that live in our body.

Consider which diseases most often require probiotic treatment along with other drugs.

First generation drugs and their effects

Intestinal inflammation is usually caused by harmful parasites or other infectious pathogenic bacteria. If a child, especially an infant, after taking an analysis, has been diagnosed with “dysbacteriosis”, then doctors prescribe drugs that contain bifidobacteria and lactobacilli, which help to compensate for the lack of beneficial bacteria.

If acute intestinal infection is present, sorbed probiotics, as well as directional drugs, help best, as only complex therapy will help to correct the situation and solve problems with the intestines rather quickly. For example Colibacterin It has a powerful effective effect in the treatment of a large number of torpid colitis.

Symptoms such as: colic in the abdomen, problems with stool or lack of stool, acetone breath, fermentation in the intestines, the problem of digestion, the presence of blood in the feces, weight loss and appetite - all this indicates the presence of dysbiosis.

Irritable bowel syndrome leads to problems with intestinal motility, along with constipation and diarrhea.

Get rid of these diseases will help such probiotics as: Bifidumbacterium and Lactobacterium, as well as their combination. They also help to cope with flatulence and stimulate the development of beneficial microorganisms. Various drugs can be produced in the form of ampoules, capsules, suppositories, tablets, and also in the form of a dry powder.

These are such drugs as:

  1. Bifidumbacterin.
  2. Lactobacterin.
  3. Colibacterin.
  4. Biobacton. Despite the fact that this tool contains only acidophilus sticks, it fights well against various pathogenic bacteria. It is prescribed for the treatment of various infections of the intestine of viral and bacterial etiology in parallel with antibacterial agents for infants from the first day of their life.
  5. Biobacton.
  6. Narine
  7. Primadofilus.

Second generation probiotics

The composition of these funds include probiotics, which contain the spores of certain types of spores of yeast fungi and bacilli. Enough of them in the large intestine helps to cope with various pathogenic bacteria and microorganisms.

  1. Baktisubtil, Flivivin BS - restore normal intestinal microflora and have antibacterial, antimicrobial and antidiarrheal action.
  2. Backspin, Sporobacterin - have an active antagonistic strain.
  3. Enterol - contains yeast-like fungi "Saccharomyces", which destroy clostridia that develop in diarrhea.
  4. Biosporin - contains spores of Licheniformis bacilli.
  5. Eubicore - Supplementswhich is enriched with both dietary fiber and yeast culture inactivated by mineral substances and various vitamins.

The third generation of probiotics (are analogues of Linex)

Here are combined several preparations containing different types of strains of several species of bacteria. They also contain additional components that enhance the action of probiotics. They have such names as:

  1. Atsipol and Atsilak - have strains of the same type of beneficial microorganisms and contain the polysaccharide of kefir fungus,
  2. Linex and Bifiform - contain strains of several types of different components.

Fourth generation probiotics

These preparations contain sorbed probiotics. This means that bifidobacteria for them are created on crushed particles of conventional activated carbon. Such remedies are capable of treating not only intestinal upset, but also more serious diseases such as: ARVI, candidiasis, influenza, lactose deficiency and other gastroenterological problems.

What are lactobacilli and why are they needed?

For centuries, these friendly microbes have been used by humans to produce a variety of food products, primarily sour-milk products (it is not for nothing that the lacto component is present in the name). During the manufacture of cheese, ryazhenka, bread and even chocolate, they destroy the harmful flora, thereby helping to preserve the freshness of the products and their suitability for consumption.

Nature initially populates lactobacilli and human intestines. It is proved that in newborns their population accounts for just over 2% of the total microflora, while there are no pathogenic microbes at all. Unlike bifidobacteria (the same “human-friendly” microorganisms), lactobacilli are found not only in the large intestine, but also in all the organs of the gastrointestinal tract (starting from the oral cavity) and even in the female vagina.

“Living” inside of us, they create an optimal balance of acidity - at the level of pH 5.5. They "try" for themselves, but thereby help the human body - they create unfavorable conditions for pathogenic bacteria and infectious agents (they don’t like the acidic environment).

Dysbacteriosis as a signal to action

Unfortunately, with age, the balance of "harmful" and "beneficial" microorganisms in the human gastrointestinal tract is significantly disturbed not in favor of the latter. The reasons for this situation may be as follows:

  • antibiotics (the most common factor),
  • living in adverse environmental conditions
  • poor nutrition,
  • frequent stress
  • a drastic change in diet (most often due to moving to another country),
  • not completely cured intestinal infection.

The results of dysbacteriosis are sad: the gastrointestinal tract is disturbed, and this is reflected in the state of the whole organism - constipation and diarrhea are accompanied by dermatological problems and a decrease in immunity.

How do lactobacilli act in humans?

In order to change the situation for the better, just need drugs for adults and children, containing lactobacilli for the intestines. They inhabit (albeit for a time) gastrointestinal tract "friendly" flora and help to achieve the desired balance:

  • inhibit the reproduction of pathogenic bacteria, including those causing diarrheal disorders (E. coli, staphylococci), as well as gastritis and ulcers (the famous Helicobacter pylori),
  • help get rid of diarrhea or constipation caused by antibiotic treatment,
  • stimulate the synthesis of immunoglobulins, interferons and antibodies to the causative agents of influenza and rotovirus diseases.

Important: getting into the intestine, lactic acid bacteria contribute to the increase in the colonies of another group of "friendly" microorganisms inside it - bifidobacteria. For this reason, it is recommended to start the normalization of microflora in the gastrointestinal tract with drugs containing lactobacilli.

Dietary supplements containing lactic acid bacteria

The list of drugs with lactobacilli to normalize the work of the intestine will be incomplete, if not mention the so-called dietary supplements. Dietary supplements are not considered to be medicines because they are released using a simplified testing scheme. As a result, the consumer receives fewer guarantees that live bacteria are there in the right concentration.

This is a drug with acidophilic lactobacilli, which can be taken in finished form or used as a leaven for preparing fermented milk drinks (depending on the form of release). Tablets and capsules are designed for adults and children from the age of three, and kefirchik is recommended to be given to infants from 5-10 days.

Dietary supplements of this format are usually called synbiotics, since they include not only probiotics (beneficial bacteria), but also a prebiotic (a substance that promotes their survival in the intestine). The Polish manufacturer uses oligofructose as the last ingredient in Maxilac. The active substances in the preparation are lacto- and bifidobacteria, as well as strains of two more bacteria - streptococcus and lactococcus.

Available in capsules (for adults) and in powder form (for children from 4 months). Cost - from 400 rubles and above.

Domestic or foreign?

Out of habit, Russian consumers trust imported, not domestic drugs. As practice shows, the principle “even more expensive, but more reliable” does not quite work with probiotics - be it lactic or bifidobacteria.

The fact is that the composition of microflora in the population of different countries differs due to the difference in climatic conditions and culinary preferences. The drugs are tested, respectively, in the state where they are produced. Consequently, the strains of microorganisms from foreign pharmacists are not fully adapted for the residents of Russia and the surrounding areas, and “work” is not as effective.

Read: How to take Ursosan with pancreatitis.

Find out what the diffusely heterogeneous structure of the pancreas means.

Why are yogurts with lactic acid bacteria not effective?

A sufficiently large amount of food is a source of lactobacilli. Of course, this is all dairy products, as well as wine, bread and vegetables, fermented in a natural way. For healthy intestines, such components of the menu guarantee a constant replenishment of the necessary bacteria, but they cannot help with dysbacteriosis.

At the same time, widely advertised yoghurts and kefir with probiotics appeared on the shelves. Perhaps they will become a worthy replacement for pharmaceutical drugs and help to overcome the effects of dysbiosis? It turns out that they cannot bring substantial benefits, as they contain living cultures in insufficient concentration. Moreover, the majority of beneficial bacteria are still dying in the stomach under the influence of hydrochloric acid and their immediate goal, the intestine, is not reached.

Watch the video: Making Lactobacillus serum Lactic acid bacteria (April 2020).